The 37.51 monoclonal antibody reacts with mouse CD28, a 45 kDa costimulatory receptor and a member of the Ig superfamily. CD28 is expressed by thymocytes, most peripheral T cells, and NK cells. CD28 is a receptor for CD80 (B7-1) and CD86 (B7-2). Signaling through CD28 augments IL-2 and IL-2 receptor expression as well as cytotoxicity of CD3-activated T cells. The 37.51 antibody has been shown to stimulate the proliferation and cytokine production by activated T and NK cells and provide a costimulatory signal for CTL induction.

產(chǎn)品名稱(chēng):InVivoMab anti-mouse CD28

反應(yīng)種屬:mouse

宿主來(lái)源:Syrian hamster

實(shí)驗(yàn)應(yīng)用:in vitro T cell stimulatioN/Activation, in vivo CD28 blockade

同種型:IgG2

免疫原:C57BL/6 mouse T cell lymphoma EL-4 cells

克隆性:Monoclonal

克隆號(hào):37.51

產(chǎn)品濃度:Lot specific,typically between 4-11 mg/ml

保存溫度:Undiluted at 4°C in the dark

運(yùn)輸溫度:Ship with adequate amount of blue ice to ensure the product remains at 4°C for the duration of transit

預(yù)期分子量:150 kDa

產(chǎn)品形式:液體

有效期:One year from the date of receipt if stored as recommended

產(chǎn)地:美國(guó)

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